7-amino-3,4-dihydro-2H-1,4-benzoxazin-3-one → 7-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-4H-benzo[1,4]oxazin-3-one

HRID 2115150

반응식

HRID 2115150 반응식
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([O:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:26])[CH2:14][NH:15][C:16]3[CH:25]=[CH:24][C:19]4[NH:20][C:21](=[O:23])[O:22][C:18]=4[CH:17]=3)[CH2:9][CH2:8]2)=[CH:4][CH:3]=1.N[C:30]1C=CC2NC(=O)COC=2C=1>CO>[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([O:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:26])[CH2:14][NH:15][C:16]3[CH:25]=[CH:24][C:19]4[NH:20][C:21](=[O:23])[CH2:30][O:22][C:18]=4[CH:17]=3)[CH2:9][CH2:8]2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 27641827-amino-3,4-dihydro-2H-1,4-benzoxazin-3-oneHCID 690999906-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-3h-benzoxazol-2-one

생성물 1

HCID 691003237-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-4H-benzo[1,4]oxazin-3-one

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The title compound is prepared from 2-chloro-1-[4-(4-chloro-phenoxy)-piperidin-1-yl]-ethanone (Example 233) and 7-amino-4H-benzo[1,4]oxazin-3-one according to the method described in Example 206. Melting Point:207-210° C. (methanol)

출처 및 근거

ORD 기록
ord-135410d446f74db6baf650c7c61d7020
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435744B2

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