Iodine → Dibenzyl phosphoroiodidate

HRID 2115633노트

반응식

HRID 2115633 반응식
[P:1]([O:18]CC1C=CC=CC=1)([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[O:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[I:26]I>C(Cl)Cl>[P:1]([I:26])(=[O:18])([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[O:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

4

반응물 2

HCID 807IodineHCID 11810300Tribenzyl phosphite

생성물 1

HCID 11101138Dibenzyl phosphoroiodidate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

반응 조건

온도
0 °C

실험 절차

To a solution of tribenzyl phosphite (0.708 g, 2.01 mmol) in CH2Cl2 (5 mL) at 0° C. was added I2 (0.49 g, 1.93 mmol). The mixture was stirred at 0° C. for 10 min or until the solution became clear and colorless. The solution was then stirred at room temperature for 10 min and used directly in the next step.

후처리

  1. stirringThe solution was then stirred at room temperature for 10 min

출처 및 근거

ORD 기록
ord-19bcfed88c2644ec8c607271ae83700c
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435861B2

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