Methylamine → HCID 68964409, 화합물

반응식

CC1C=CC(S(O[CH2:12][CH:13]2[CH2:17][C:16]3[CH:18]=[CH:19][C:20]([Cl:29])=[C:21]([C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=4[CH3:28])[C:15]=3[O:14]2)(=O)=O)=CC=1.[CH3:30][NH2:31]>>[Cl:29][C:20]1[CH:19]=[CH:18][C:16]2[CH2:17][CH:13]([CH2:12][NH:31][CH3:30])[O:14][C:15]=2[C:21]=1[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[CH3:28]

참가 물질

반응물 2

HCID 6329Methylamine

HCID 86599288HCID 86599288, 화합물

생성물 1

HCID 68964409HCID 68964409, 화합물

실험 절차

The title compound was prepared (0.02 g, 27%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (±)-[6-chloro-7-(2-methylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate (0.1 g, 0.23 mmol) and methylamine (0.24 g, 7.8 mmol). mp 158-160° C.

출처 및 근거

ORD 기록: ord-a24709422664410eb903d6c79d3f3f99
출처 데이터셋: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07435837B2

반응 노트

불러오는 중…