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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2116909생성일: 2026년 10월 25일

2-Chloro-3-(trifluoromethyl)pyridine → 2-(4-(4,5-Bis-(4-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)-5,6-dihydropyridin-1(2H)-yl)-3-(trifluoromethyl)pyridine

https://huagongshe.com/reaction/2116909

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-3-(trifluoromethyl)pyridineHCID 589833—
반응물4-[4,5-Bis-(4-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-1,2,3,6-tetrahydropyridineHCID 58625818—
생성물2-(4-(4,5-Bis-(4-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)-5,6-dihydropyridin-1(2H)-yl)-3-(trifluoromethyl)pyridineHCID 11664273—

반응 단계

4-[4,5-Bis-(4-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-1,2,3,6-tetrahydropyridine from step (b) above reacted with 2-chloro-3-trifluoromethyl-pyridine (352 mg, 1.95 mmol, TCI America) under the condition of Example 22(d) to give the title compound as a light-yellow solid. MS (ESI, positive ion) m/z: 583 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07439360B2
출처 데이터셋uspto-grants-2008_10
ORD IDord-7a47e49fe73340bfa085bb8b3b2f028d
출처 메모uspto-grants-2008_10