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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2117400생성일: 2026년 10월 26일

2-Isopropoxy-5-methylsulfonylbenzoic acid → (2-Isopropoxy-5-methanesulfonyl-phenyl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone

https://huagongshe.com/reaction/2117400

반응식

참여 물질

역할이름HCID투입량
반응물2-Isopropoxy-5-methylsulfonylbenzoic acidHCID 21100237—
반응물2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochlorideHCID 57445256—
생성물(2-Isopropoxy-5-methanesulfonyl-phenyl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanoneHCID 57445255—

반응 단계

Prepared in analogy to example 1.1 from 2-trifluoromethyl-5,6,7,8-tetrahydro-[1,6]naphthyridine hydrochloride (CA [741736-98-1]; WO2004069162) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1). MS (m/e): 443.5 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07442710B2
출처 데이터셋uspto-grants-2008_10
ORD IDord-6f91acfb10e6475ca8a3730741327125
출처 메모uspto-grants-2008_10