8-Chloro-1,2,3,4-tetrahydroisoquinoline → HCID 11545983, 화합물

HRID 2117422노트

반응식

HRID 2117422 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH2:10][NH:9][CH2:8][CH2:7]2.[CH:12]([O:15][C:16]1[CH:24]=[CH:23][C:22]([S:25]([CH3:28])(=[O:27])=[O:26])=[CH:21][C:17]=1[C:18](O)=[O:19])([CH3:14])[CH3:13]>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH2:10][N:9]([C:18]([C:17]1[CH:21]=[C:22]([S:25]([CH3:28])(=[O:27])=[O:26])[CH:23]=[CH:24][C:16]=1[O:15][CH:12]([CH3:14])[CH3:13])=[O:19])[CH2:8][CH2:7]2

참가 물질

3

반응물 2

HCID 125950718-Chloro-1,2,3,4-tetrahydroisoquinolineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

생성물 1

HCID 11545983HCID 11545983, 화합물

실험 절차

Prepared in analogy to example 1.1 from 8-chloro-1,2,3,4-tetrahydro-isoquinoline (CA [61563-33-5]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

출처 및 근거

ORD 기록
ord-a1cf20c9ad4e42a19b58d51296103a1a
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07442710B2

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