5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline → HCID 57445264, 화합물

반응식

[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][NH:6][CH2:7]2.[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19](O)=[O:20])([CH3:15])[CH3:14]>>[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([C:19]([C:18]1[CH:22]=[C:23]([S:26]([CH3:29])(=[O:28])=[O:27])[CH:24]=[CH:25][C:17]=1[O:16][CH:13]([CH3:15])[CH3:14])=[O:20])[CH2:7]2

참가 물질

반응물 2

HCID 125950735,7-Dichloro-1,2,3,4-tetrahydroisoquinoline

HCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

생성물 1

HCID 57445264HCID 57445264, 화합물

실험 절차

Prepared in analogy to example 1.1 from 5,7-dichloro-1,2,3,4-tetrahydro-isoquinoline (CA [89315-56-0]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

출처 및 근거

ORD 기록: ord-6e810424eec64f46b71cca30decad8a6
출처 데이터셋: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07442710B2

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