6-Chloro-1,2,3,4-tetrahydroisoquinoline → (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-diethylamino-5-methanesulfonyl-phenyl)-methanone
반응식
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][NH:7][CH2:6][CH2:5]2.[CH2:12]([N:14]([CH2:28][CH3:29])[C:15]1[CH:23]=[CH:22][C:21]([S:24]([CH3:27])(=[O:26])=[O:25])=[CH:20][C:16]=1[C:17](O)=[O:18])[CH3:13]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][N:7]([C:17]([C:16]1[CH:20]=[C:21]([S:24]([CH3:27])(=[O:26])=[O:25])[CH:22]=[CH:23][C:15]=1[N:14]([CH2:28][CH3:29])[CH2:12][CH3:13])=[O:18])[CH2:6][CH2:5]2참가 물질
3
실험 절차
Prepared in analogy to example 1.1 from 6-chloro-1,2,3,4-tetrahydro-isoquinoline (CA [33537-99-4]) and 2-diethylamino-5-methanesulfonyl-benzoic acid (example 2.6).
출처 및 근거
- ORD 기록
- ord-b91754ee9c9d48899f1f57039baab1a1
- 출처 데이터셋
- uspto-grants-2008_10