4-(3-Bromophenyl)but-3-yn-1-ol → 4-(3-Bromophenyl)butan-1-ol

HRID 2117666노트

반응식

HRID 2117666 반응식
[Br:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][CH2:10][CH2:11][OH:12])[CH:5]=[CH:6][CH:7]=1>C(O)C.[Pt]=O>[Br:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 1

HCID 218954424-(3-Bromophenyl)but-3-yn-1-ol

생성물 1

HCID 218954894-(3-Bromophenyl)butan-1-ol수율 84.2%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 702Ethanol용매

실험 절차

A solution of 4-(3-bromophenyl)but-3-yn-1-ol (21 g) in ethanol (1000 ml) was hydrogenated over platinum oxide (500 mg) for 4 h. The catalyst was removed by filtration and the filtrate was evaporated to give the title compound (18 g) tlc (SiO2) diethyl ether Rf=0.38.

후처리

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-80fc678aac90454082f540f913c17e2e
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07442719B2

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