HCID 53851186, 화합물 → HCID 54249876, 화합물

HRID 2118460노트

반응식

HRID 2118460 반응식
[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[NH:9][C:10](=[O:25])[C:11]([NH:14]C(OCC1C=CC=CC=1)=O)([CH3:13])[CH3:12]>CO.[Pd]>[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][C:4]([CH3:7])([CH3:8])[CH:3]1[NH:9][C:10](=[O:25])[C:11]([NH2:14])([CH3:13])[CH3:12]

참가 물질

4

반응물 1

HCID 53851186HCID 53851186, 화합물

생성물 1

HCID 54249876HCID 54249876, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl amide is dissolved in CH3OH and is hydrogenated over 5% Pd/C in a Parr hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concentrated to yield 2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl amide.

후처리

  1. filtrationis filtered through Celite
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-32a3da75e8b142cbbd4a66ea53d60196
출처 데이터셋
uspto-grants-1987_07
특허 번호
US04678674

반응 노트

불러오는 중…