Benzene, 1-(chloromethyl)-2-fluoro- → 2-(2-Fluorobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolinium chloride
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[CH:9]=[N:8][CH2:7][CH2:6]2.[F:15][C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18][Cl:19]>C(Cl)CCl>[Cl-:19].[F:15][C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18][N+:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:9]=1참가 물질
4
실험 절차
The title compound is prepared analogously to Example A from 6,7-dimethoxy-3,4-dihydroisoquinoline and 2-fluorobenzyl chloride in ethylene chloride. Melting point: 196°-198° C. (Decomp.)
출처 및 근거
- ORD 기록
- ord-bad56d8baeea49e2b1c16761ec36dc38
- 출처 데이터셋
- uspto-grants-1987_07
- 특허 번호
- US04678792
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