Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Amino-4-vinylisoindolinone → 7-Amino-4-ethylisoindolinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Amino-4-vinylisoindolinone | HCID 68488659 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 7-Amino-4-ethylisoindolinone | HCID 68490969 | 102.8% |
반응 단계
7-Amino-4-vinylisoindolinone (50.0 mg, 0.287 mmol) was dissolved in DMF (2.5 mL), and the solution was added with 10% Pd—C (10 mg) followed by stirring at room temperature for 1.8 hours under normal pressure and hydrogen atmosphere. The reaction mixture was filtered using Celite and the solvent of the filtrate was evaporated under reduced pressure to obtain 7-amino-4-ethylisoindolinone (52.0 mg, quantitative).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745641B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-9b574fe409a9418d963834a7bf341de1 |
| 출처 메모 | uspto-grants-2010_06 |