HCID 14203475, 화합물 → 2-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

HRID 2119128노트

반응식

HRID 2119128 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

참가 물질

4

반응물 1

HCID 14203475HCID 14203475, 화합물

생성물 1

HCID 147428442-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the presence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen has been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

후처리

  1. customof hydrogen has been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

출처 및 근거

ORD 기록
ord-b0f7db73b5ed48c1a1c0fef1756c3bee
출처 데이터셋
uspto-grants-1987_07
특허 번호
US04683232

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