2-Bromo-1-(2-ethylphenyl)ethan-1-one → {3-[5-(2-Ethyl-benzoyl)-thiazol-2-ylamino]-propyl}-carbamic Acid tert-butyl Ester
반응식
[C:1]([O:5][C:6](=[O:19])[NH:7][CH2:8][CH2:9][CH2:10][NH:11][C:12]([N:14]=[CH:15]N(C)C)=[S:13])([CH3:4])([CH3:3])[CH3:2].[CH2:20]([C:22]1[CH:31]=[CH:30][CH:29]=[CH:28][C:23]=1[C:24](=[O:27])[CH2:25]Br)[CH3:21]>>[C:1]([O:5][C:6](=[O:19])[NH:7][CH2:8][CH2:9][CH2:10][NH:11][C:12]1[S:13][C:25]([C:24](=[O:27])[C:23]2[CH:28]=[CH:29][CH:30]=[CH:31][C:22]=2[CH2:20][CH3:21])=[CH:15][N:14]=1)([CH3:2])([CH3:3])[CH3:4]참가 물질
3
실험 절차
The title compound was synthesised from [3-(3-Dimethylaminomethylene-thioureido)-propyl]-carbamic acid tert-butyl ester and 2-ethyl phenacylbromide according to the procedure described for Example 25. MS (m/e): 389.9 (MH+, 100%).
출처 및 근거
- ORD 기록
- ord-f17741a37dae4acfbda85574c7287e31
- 출처 데이터셋
- uspto-grants-2004_02