Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 7-Benzyl-1-methyl-1,4-dihydro-pyrazolo[4,3-b]quinolin-9-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | 7-benzyl-9-chloro-1-methyl-1H-pyrazolo[4,3-b]quinoline | HCID 23442381 | — |
| 생성물 | 7-Benzyl-1-methyl-1,4-dihydro-pyrazolo[4,3-b]quinolin-9-one | HCID 9857150 | 96% |
반응 단계
A mixture of 7-benzyl-9-chloro-1-methyl-1H-pyrazolo[4,3-b]quinoline (EXAMPLE 11, step 2, 1.00 g, 3.25 mmol) in 50% aqueous acetic acid (20 ml) was refluxed for 6 h. After cooling to room temperature, the formed solid was collected by filtration to give 905 mg (96%) of the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06686373B2 |
| 출처 데이터셋 | uspto-grants-2004_02 |
| ORD ID | ord-29f4e4f88cb142d39c248e59a02d885a |
| 출처 메모 | uspto-grants-2004_02 |