Water → 3-(Azidomethyl)-5-methyl-1,2-oxazole

HRID 2119945노트

반응식

HRID 2119945 반응식
Br[CH2:2][C:3]1[CH:7]=[C:6]([CH3:8])[O:5][N:4]=1.[N-:9]=[N+:10]=[N-:11].[Na+].O>CC(C)=O>[N:9]([CH2:2][C:3]1[CH:7]=[C:6]([CH3:8])[O:5][N:4]=1)=[N+:10]=[N-:11]

참가 물질

5

반응물 3

HCID 962WaterHCID 33557Sodium AzideHCID 27763043-(Bromomethyl)-5-methylisoxazole

생성물 1

HCID 234409373-(Azidomethyl)-5-methyl-1,2-oxazole

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To a solution of the 3-bromomethyl-5-methyl-isoxazole in acetone is added NaN3 at rt. The reaction mixture is then stirred for about 48 h. Then, the reaction mixture is poured into water and extracted with EtOAc, dried and evaporated.

후처리

  1. extractionextracted with EtOAc
  2. customdried
  3. customevaporated

출처 및 근거

ORD 기록
ord-d40a14bb0478455e98f221682ad6f4aa
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06686352B2

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