Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 3-Butyl-6-(isopropylamino)-phthalide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | 6-Amino-3-butyl-phthalide | HCID 9877706 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Butyl-6-(isopropylamino)-phthalide | HCID 9964853 | — |
반응 단계
To a solution of 4.1 g (20.0 mmol) of compound obtained in Example 4 in 4 ml of acetone and 96 ml of anhydrous ethanol there is added 10% Pd—C catalyst. The mixture is hydrogenated under a hydrogen pressure of 3-3.5 kg/cm2. After the absorption of hydrogen is complete, the catalyst is filtered off and the filtrate is concentrated in vacuo to dryness. The residue is crystallised from dilute ethanol to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06689808B2 |
| 출처 데이터셋 | uspto-grants-2004_02 |
| ORD ID | ord-8484c0784fa546faa001dddbf1c438e2 |
| 출처 메모 | uspto-grants-2004_02 |