Nitric Acid → 6-Acetamido-3-butyl-5-nitro-phthalide

HRID 2120189노트

반응식

HRID 2120189 반응식
[N+:1]([O-:4])(O)=[O:2].[C:5]([NH:8][C:9]1[CH:18]=[C:17]2[C:12]([CH:13]([CH2:19][CH2:20][CH2:21][CH3:22])[O:14][C:15]2=[O:16])=[CH:11][CH:10]=1)(=[O:7])[CH3:6]>>[C:5]([NH:8][C:9]1[CH:18]=[C:17]2[C:12]([CH:13]([CH2:19][CH2:20][CH2:21][CH3:22])[O:14][C:15]2=[O:16])=[CH:11][C:10]=1[N+:1]([O-:4])=[O:2])(=[O:7])[CH3:6]

참가 물질

3

반응물 2

HCID 944Nitric AcidHCID 232747896-Acetamido-3-butyl-phthalide

생성물 1

HCID 234391106-Acetamido-3-butyl-5-nitro-phthalide

실험 절차

To 100 ml of stirred and ice-cold turning nitric acid (sp. gr. 1.50) there are added, in portions, 59 g (0.288 mol) of compound obtained in Example 7 with the temperature below 10° C. The resulting clear solution is put aside at room temperature overnight. The reaction material is poured into crushed ice, and the solid is filtered, washed with water, dried and crystallised from ethanol, giving the title compound.

후처리

  1. additionThe reaction material is poured
  2. custominto crushed ice
  3. filtrationthe solid is filtered
  4. washwashed with water
  5. customdried
  6. customcrystallised from ethanol

출처 및 근거

ORD 기록
ord-aae83b5e83bf44a2b51f533fcb26b36a
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06689808B2

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