Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Salicylaldehyde → 3-(2-Hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Salicylaldehyde | HCID 6998 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 6-Thiophen-3-yl-1,3-dihydroindol-2-one | HCID 23439027 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(2-Hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one | HCID 53674365 | 69% |
반응 단계
A mixture of 6-thiophen-3-yl-1,3-dihydroindol-2-one (100 mg, 0.5 mmol), 2-hyroxy-benzaldehyde (60 mg, 0.5 mmol) and piperidine (0.23 mL) in ethanol (4 mL) was stirred at reflux overnight. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 110 mg (69%) of 3-(2-hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one as yellow-red crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06689806B1 |
| 출처 데이터셋 | uspto-grants-2004_02 |
| ORD ID | ord-810dfb8b26d54e3086376f582cc18ff8 |
| 출처 메모 | uspto-grants-2004_02 |