Pyridine → 3,5-Dinitrophenyl cinnamate

HRID 2120312노트

반응식

HRID 2120312 반응식
[C:1](Cl)(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[N+:12]([C:15]1[CH:16]=[C:17]([OH:24])[CH:18]=[C:19]([N+:21]([O-:23])=[O:22])[CH:20]=1)([O-:14])=[O:13].N1C=CC=CC=1>CC(C)=O>[C:1]([O:24][C:17]1[CH:16]=[C:15]([N+:12]([O-:14])=[O:13])[CH:20]=[C:19]([N+:21]([O-:23])=[O:22])[CH:18]=1)(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

5

반응물 3

HCID 1049PyridineHCID 114593,5-DinitrophenolHCID 660233-Phenylprop-2-enoyl chloride

생성물 1

HCID 3182223,5-Dinitrophenyl cinnamate수율 71.6%

시약·촉매·용매 1

HCID 180Acetone용매3회

반응 조건

온도
60 °C

실험 절차

66.64 g (0.4 mole) of cinnamoyl chloride and 300 g of methyl ketone (hereinafter referred to as MEK) were placed in a reaction vessel to be stirred by heating at 60° C. under a nitrogen current. 73.64 g (0.4 mole) of 3,5-dinitrophenol, 50 g of pyridine, and 500 g of MEK were added dropwise to the above reaction vessel using a dropping funnel. After that, reflux stirring was conducted for approximately 2 hours under a nitrogen current. After the completion of the reaction, the precipitate was separated by filtration. The filtrate was concentrated until crystals separated out and poured into methanol. 90 g of light yellow colored needle-like crystals (2, 4-dinitrophenyl cinnamate) were yielded.

후처리

  1. customwere placed in a reaction vessel
  2. temperatureAfter that, reflux
  3. stirringstirring
  4. customAfter the completion of the reaction
  5. customthe precipitate was separated by filtration
  6. concentrationThe filtrate was concentrated until crystals
  7. customseparated out and
  8. additionpoured into methanol

출처 및 근거

ORD 기록
ord-0fec1c9e49e14b37bfa8323f97eacba2
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06689899B2

반응 노트

불러오는 중…