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Pyridine → HCID 78569128, 화합물

HRID 2120319
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HRID 2120319 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][CH:14]=1)[CH:7]=[CH:8][C:9](Cl)=[O:10])([O-:3])=[O:2].[N+:15]([C:18]1[CH:19]=[C:20]([OH:24])[CH:21]=[CH:22][CH:23]=1)([O-:17])=[O:16].N1C=CC=CC=1>CC(C)=O>[N+:15]([C:18]1[CH:19]=[C:20]([O:24][C:9](=[O:10])[CH:8]=[CH:7][C:6]2[CH:12]=[CH:13][CH:14]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[CH:21]=[CH:22][CH:23]=1)([O-:17])=[O:16]
참가 물질반응 조건실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 1049PyridineHCID 111373-NitrophenolHCID 534112912-Propenoyl chloride, 3-(3-nitrophenyl)-, (E)-

생성물 1

HCID 78569128HCID 78569128, 화합물수율 90.2%

시약·촉매·용매 1

HCID 180Acetone용매2회

반응 조건

온도
50 °C

실험 절차

64.5 g (0.3 mole) of 3-nitrocinnamoyl chloride and 300 g of acetone were placed in a reaction vessel and stirred at 50° C. under a nitrogen current. 41.73 g (0.3 mole) of 3-nitrophenol, 60 g of pyridine, and 300 g of acetone were added dropwise to the above reaction vessel using a dropping funnel. After the completion of the addition, the reaction mixtures were stirred under a nitrogen current for 2 hours. After the reaction, the solid obtained by concentrating the solution was washed by water and dried. 85 g of light yellow colored needle-like crystals ((3-nitrophenyl)-3-cinnamate) was yielded.

후처리

  1. additionAfter the completion of the addition
  2. customthe reaction mixtures
  3. stirringwere stirred under a nitrogen current for 2 hours
  4. customAfter the reaction
  5. customthe solid obtained
  6. concentrationby concentrating the solution
  7. washwas washed by water
  8. customdried

출처 및 근거

ORD 기록
ord-213c7955673a43eb9636cebfb8d197bc
출처 데이터셋
uspto-grants-2004_02
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US06689899B2

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