4-Nitrophenol → 2-Propanol, 1,3-bis(p-nitrophenoxy)-

HRID 2120321노트

반응식

HRID 2120321 반응식
[CH:1]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][CH:4]=[C:3]([OH:10])[CH:2]=1>C1(C)C(C)=CC=CC=1>[N+:7]([C:6]1[CH:5]=[CH:4][C:3]([O:10][CH2:2][CH:3]([OH:10])[CH2:4][O:10][C:3]2[CH:4]=[CH:5][C:6]([N+:7]([O-:9])=[O:8])=[CH:1][CH:2]=2)=[CH:2][CH:1]=1)([O-:9])=[O:8]

참가 물질

3

반응물 1

HCID 9804-Nitrophenol

생성물 1

HCID 4590272-Propanol, 1,3-bis(p-nitrophenoxy)-

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

76.5 g (0.55 mole) of p-nitrophenol, 32.3 g (0.25 mole) of glycerol-αα′-dichlorohydrin, and 500 ml of xylene were added to a reaction solution, and the reaction mixtures were heated with stirring under a nitrogen current. After dissolving the solid, 345 g (2.5 moles) of potassium carbonate anhydride was added, and the reaction mixtures were refluxed with stirring for 12 hours. The reacted solution was separated by filtration while it was warm. After cooling, hexane was added to the filtrate. A yellow viscous liquid was obtained. After column purification and drying this liquid, a 55 g-yellow viscous liquid (1,3-bis (4-nitrophenoxy)-2-propyl alcohol) was obtained.

후처리

  1. customthe reaction mixtures
  2. temperaturewere heated
  3. additionwas added
  4. customthe reaction mixtures
  5. temperaturewere refluxed
  6. stirringwith stirring for 12 hours
  7. customThe reacted solution was separated by filtration while it
  8. temperaturewas warm
  9. temperatureAfter cooling
  10. additionhexane was added to the filtrate
  11. customA yellow viscous liquid was obtained
  12. customAfter column purification
  13. customdrying this liquid

출처 및 근거

ORD 기록
ord-3a093f462d024b53bfa3715945a97110
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06689899B2

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