Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → 5-Bromomethyl-2-phenylbenzoxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-Phenyl-5-methylbenzoxazole | HCID 81919 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 5-Bromomethyl-2-phenylbenzoxazole | HCID 22062830 | 70.6% |
반응 단계
5-methyl-2-phenylbenzoxazole 55 (1.23 g, 5.8 mmol) and NBS (1.17 g, 6.5 mmol) were dissolved in carbon tetrachloride (20 ml). The mixture was evacuated and flushed with argon. AIBN (ca. 5 mg) was added and the mixture heated at reflux and irradiated with a sun lamp for 3 hrs. The solvent was evaporated under reduced pressure and the residue purified by chromatography to yield 1.18 g of 5-bromomethyl-2-phenylbenzoxazole 56.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06693098B2 |
| 출처 데이터셋 | uspto-grants-2004_02 |
| ORD ID | ord-a373492fe5344d06b44ae78302506fbc |
| 출처 메모 | uspto-grants-2004_02 |