참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 3-(4-Chloro-3-nitrophenyl)acrylic acid | HCID 614919 | — |
| 촉매 | Platinum sulfide (PtS) | HCID 82861 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-(4-Chloro-3-aminophenyl)propionic acid | HCID 12388282 | 99.8% |
반응 단계
A slurry of 4-chloro-3-nitrocinnamic acid (12.2 g, 53.2 mmol), ethyl alcohol (50 mL) and ethyl acetate (20 mL) was treated with 5% Platinum sulfide on carbon (0.6 g) and was placed in a Parr autoclave. The autoclave was placed under a hydrogen atmosphere and heated overnight at 50° C. After cooling to room temperature, the reaction mixture was filtered through celite, and was concentrated in vacuo to yield 10.6 g of 3-(4-chloro-3-aminophenyl)propionic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06693208B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_02 |
|---|
| ORD ID | ord-cdfe74b4c4d9483d86cee73568f571cc |
|---|
| 출처 메모 | uspto-grants-2004_02 |
|---|
