methyl (2S)-2-amino-4-(methylsulfanyl)butanoate → 4-Fluoro-2-phenylbenzoyl Methionine Methyl Ester

HRID 2121117노트

반응식

HRID 2121117 반응식
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:3]=1.[CH3:17][O:18][C:19](=[O:26])[C@H:20]([CH2:22][CH2:23][S:24][CH3:25])[NH2:21]>>[CH3:17][O:18][C:19](=[O:26])[C@H:20]([CH2:22][CH2:23][S:24][CH3:25])[NH:21][C:6](=[O:8])[C:5]1[CH:9]=[CH:10][C:2]([F:1])=[CH:3][C:4]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

3

반응물 2

HCID 64684methyl (2S)-2-amino-4-(methylsulfanyl)butanoateHCID 167687084-Fluoro-2-phenylbenzoic acid

생성물 1

HCID 206228304-Fluoro-2-phenylbenzoyl Methionine Methyl Ester

실험 절차

The resultant product from Example 13B is coupled to methionine methyl ester according to the procedure of Example 1C to give the tide compound.

후처리

  1. customto give the tide compound

출처 및 근거

ORD 기록
ord-e440def421314c6e856863b454be23e0
출처 데이터셋
uspto-grants-2004_02
특허 번호
US06693123B2

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