Dimethylamine → 4-(5-Cyano-7-isopropyl-1,3-benzoxazol-2-yl)-N-({1-[2-(dimethylamino)pyrimidin-4-yl]piperidin-4-yl}methyl)benzamide

반응식

[CH3:38][NH:39][CH3:40].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][CH:11]([CH2:14][NH:15][C:16]([c:17]3[cH:18][cH:19][c:20](-[c:23]4[o:24][c:25]5[c:26]([n:27]4)[cH:28][c:29]([C:35]#[N:36])[cH:30][c:31]5[CH:32]([CH3:33])[CH3:34])[cH:21][cH:22]3)=[O:37])[CH2:12][CH2:13]2)[n:7]1>>[c:2]1([N:39]([CH3:38])[CH3:40])[n:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][CH:11]([CH2:14][NH:15][C:16]([c:17]3[cH:18][cH:19][c:20](-[c:23]4[o:24][c:25]5[c:26]([n:27]4)[cH:28][c:29]([C:35]#[N:36])[cH:30][c:31]5[CH:32]([CH3:33])[CH3:34])[cH:21][cH:22]3)=[O:37])[CH2:12][CH2:13]2)[n:7]1

참가 물질

반응물 2

HCID 674Dimethylamine

HCID 25169790N-{[1-(2-Chloropyrimidin-4-yl)piperidin-4-yl]methyl}-4-(5-cyano-7-isopropyl-1,3-benzoxazol-2-yl)benzamide

생성물 1

HCID 251700104-(5-Cyano-7-isopropyl-1,3-benzoxazol-2-yl)-N-({1-[2-(dimethylamino)pyrimidin-4-yl]piperidin-4-yl}methyl)benzamide

출처 및 근거

ORD 기록: ord-8763cdcf8c7646b4857dcfe6e4d016f1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…