2-(6-chloro-2-oxo-3H-benzimidazol-1-yl)-2-(4-methoxyphenyl)acetic acid → 5-chloro-3-[1-(4-methoxyphenyl)-2-oxo-2-[3-(4-propylpiperazin-1-yl)pyrrolidin-1-yl]ethyl]-1H-benzimidazol-2-one

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([CH:7]([c:8]3[cH:9][cH:10][cH:11][cH:26][cH:27]3)[C:28]([N:12]3[CH2:13][CH:14]([N:17]4[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH3:25])[CH2:21][CH2:22]4)[CH2:15][CH2:16]3)=[O:29])[c:30](=[O:31])[nH:32][c:33]2[cH:34]1.[Cl:35][c:36]1[cH:37][cH:38][c:39]2[c:40]([n:41]([CH:45]([C:46](=[O:47])[OH:48])[c:49]3[cH:50][cH:51][c:52]([O:55][CH3:56])[cH:53][cH:54]3)[c:42](=[O:44])[nH:43]2)[cH:57]1>>[N:12]1([C:46]([CH:45]([n:41]2[c:40]3[c:39]([cH:38][cH:37][c:36]([Cl:35])[cH:57]3)[nH:43][c:42]2=[O:44])[c:49]2[cH:50][cH:51][c:52]([O:55][CH3:56])[cH:53][cH:54]2)=[O:47])[CH2:13][CH:14]([N:17]2[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH3:25])[CH2:21][CH2:22]2)[CH2:15][CH2:16]1