Dimethylformamide → 3-methyl-1-[4-(7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile

반응식

[Br:1][CH2:2][CH:3]1[CH2:4][C:5]([n:7]2[n:8][cH:9][c:10](-[c:12]3[c:13]4[c:14]([n:15][cH:16][n:17]3)[n:18]([CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:19][cH:20]4)[cH:11]2)([CH2:29][C:30]#[N:31])[CH2:6]1.[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[CH3:2][CH:3]1[CH2:4][C:5]([n:7]2[n:8][cH:9][c:10](-[c:12]3[c:13]4[c:14]([n:15][cH:16][n:17]3)[n:18]([CH2:21][O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:19][cH:20]4)[cH:11]2)([CH2:29][C:30]#[N:31])[CH2:6]1

참가 물질

반응물 2

HCID 6228Dimethylformamide

HCID 670172173-(bromomethyl)-1-[4-(7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile

생성물 1

HCID 670172343-methyl-1-[4-(7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile

출처 및 근거

ORD 기록: ord-80e56be4bc1a4918b232aac888bac150
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

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