5-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid → 5-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [2-chloro-5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-thiophen-3-yl]-amide

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20](=[O:21])[OH:22])[cH:6][cH:7]1.[OH:23][CH2:24][C:25]([CH3:26])([CH3:27])[NH:28][S:29](=[O:30])(=[O:31])[c:32]1[s:33][c:34]([Cl:38])[c:35]([NH2:37])[cH:36]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]4[CH2:15][CH2:16]4)[cH:13]2)[n:17][cH:18][c:19]3[C:20](=[O:21])[NH:37][c:35]2[c:34]([Cl:38])[s:33][c:32]([S:29]([NH:28][C:25]([CH2:24][OH:23])([CH3:26])[CH3:27])(=[O:30])=[O:31])[cH:36]2)[cH:6][cH:7]1