Dichloromethane → 5-{1-[4-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiophene-2-sulfonic acid amide

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[n:15][cH:16][n:17](-[c:19]3[n:20][c:21](-[c:29]4[cH:30][cH:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]3)[cH:18]2)[cH:12][cH:13]1.[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[n:15][cH:16][n:17](-[c:19]3[n:20][c:21](-[c:29]4[cH:30][cH:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[n:24]3)[cH:18]2)[cH:12][cH:13]1