2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 2-{[6-(1-Cyano-3-hydroxypropyl)pyridin-2-yl]amino}-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

HRID 2133678

반응식

HRID 2133678 반응식
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]([C:9]#[N:10])[CH2:11][CH2:12][OH:13])[n:7]1.[NH2:14][c:15]1[s:16][c:17](-[c:23]2[c:24]([F:33])[cH:25][c:26]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:27][cH:28]2)[cH:18][c:19]1[C:20](=[O:21])[NH2:22]>>[c:2]1([NH:14][c:15]2[s:16][c:17](-[c:23]3[c:24]([F:33])[cH:25][c:26]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:27][cH:28]3)[cH:18][c:19]2[C:20](=[O:21])[NH2:22])[cH:3][cH:4][cH:5][c:6]([CH:8]([C:9]#[N:10])[CH2:11][CH2:12][OH:13])[n:7]1

참가 물질

3

반응물 2

HCID 582166382-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 595255742-(6-Bromopyridin-2-yl)-4-hydroxybutanenitrile

생성물 1

HCID 595257632-{[6-(1-Cyano-3-hydroxypropyl)pyridin-2-yl]amino}-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

출처 및 근거

ORD 기록
ord-6305ba7bc06e4beea0270223bf748990
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

연결된 노트

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