Dichloromethane → 2-Amino-4-(4-cyclopropylcarbamoyl-phenyl)-thiazole-5-carboxylic acid methyl ester

반응식

[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6](-[c:18]2[cH:19][cH:20][c:21]([C:24]([NH:25][CH:26]3[CH2:27][CH2:28]3)=[O:29])[cH:22][cH:23]2)[n:7][c:8]([NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[s:9]1.[Cl:37][CH2:38][Cl:39].[F:30][C:31]([F:32])([F:33])[C:34]([OH:35])=[O:36]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6](-[c:18]2[cH:19][cH:20][c:21]([C:24]([NH:25][CH:26]3[CH2:27][CH2:28]3)=[O:29])[cH:22][cH:23]2)[n:7][c:8]([NH2:10])[s:9]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 866164462-tert-Butoxycarbonylamino-4-(4-cyclopropylcarbamoyl-phenyl)-thiazole-5-carboxylic acid methyl ester

생성물 1

HCID 866164452-Amino-4-(4-cyclopropylcarbamoyl-phenyl)-thiazole-5-carboxylic acid methyl ester

출처 및 근거

ORD 기록: ord-e1d0ab0c76fb4fd891a99fae357a6be9
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

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