(R)-4-(4-Aminobenzyl)-2-oxazolidinone → ethyl 8-(2,3-dihydro-1H-inden-5-yl)-5-oxo-2-[4-[(2-oxo-1,3-oxazolidin-4-yl)methyl]anilino]pyrido[2,3-d]pyrimidine-6-carboxylate

반응식

[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[c:20]1[c:21](=[O:43])[c:22]2[c:23]([n:24][c:25]([S:28]([CH3:29])(=[O:30])=[O:31])[n:26][cH:27]2)[n:32](-[c:34]2[cH:35][c:36]3[c:40]([cH:41][cH:42]2)[CH2:39][CH2:38][CH2:37]3)[cH:33]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[NH:8][C:9](=[O:12])[O:10][CH2:11]2)[cH:13][cH:14]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[NH:8][C:9](=[O:12])[O:10][CH2:11]2)[cH:13][cH:14]1)[c:25]1[n:24][c:23]2[c:22]([c:21](=[O:43])[c:20]([C:18]([O:17][CH2:15][CH3:16])=[O:19])[cH:33][n:32]2-[c:34]2[cH:35][c:36]3[c:40]([cH:41][cH:42]2)[CH2:39][CH2:38][CH2:37]3)[cH:27][n:26]1

참가 물질

반응물 2

HCID 11842283(R)-4-(4-Aminobenzyl)-2-oxazolidinone

HCID 252229828-Indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

생성물 1

HCID 68676882ethyl 8-(2,3-dihydro-1H-inden-5-yl)-5-oxo-2-[4-[(2-oxo-1,3-oxazolidin-4-yl)methyl]anilino]pyrido[2,3-d]pyrimidine-6-carboxylate

출처 및 근거

ORD 기록: ord-525b27f187ad43b48e4f4f4ae0899012
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

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