Benzyl Bromide → 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid

HRID 21354

반응식

[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][CH:7]([C:12]([OH:14])=[O:13])[CH2:6][CH2:5]2.[CH2:15](Br)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[OH-].[K+]>>[CH2:15]([O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][CH:7]([C:12]([OH:14])=[O:13])[CH2:6][CH2:5]2)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

반응물 3

HCID 7498Benzyl Bromide

HCID 14797Potassium Hydroxide

HCID 190700016-Hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid

생성물 1

HCID 190699736-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid

실험 절차

The 1,2,3,4-tetrahydro-6-hydroxynaphthalene-2-carboxylic acid obtained in the above is caused to react with benzyl bromide in the presence of potassium hydroxide, to obtain 1,2,3,4-tetrahydro-6-benzyloxynaphthalene-2-carboxylic acid. The compound thus obtained is heated under reflux in the presence of an acid catalyst to obtain 1,2,3,4-tetrahydro-6-benzyloxynaphthalene-2-carboxylic acid methyl ester.

출처 및 근거

ORD 기록: ord-2610e29e13d34bda911c6dcb2de9c970
출처 데이터셋: uspto-grants-1995_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05422039

연결된 노트

불러오는 중…