5-bromo-N,N-dimethylpyrimidine-2-carboxamide → 5-[3-(dibenzylamino)-3,4-dihydro-2H-chromen-5-yl]-N,N-dimethylpyrimidine-2-carboxamide

반응식

[Br:35][c:36]1[cH:37][n:38][c:39]([C:42](=[O:43])[N:44]([CH3:45])[CH3:46])[n:40][cH:41]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][O:11][c:12]2[cH:13][cH:14][cH:15][c:16]([B:19]3[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]3)[c:17]2[CH2:18]1)[CH2:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][O:11][c:12]2[cH:13][cH:14][cH:15][c:16](-[c:36]3[cH:37][n:38][c:39]([C:42](=[O:43])[N:44]([CH3:45])[CH3:46])[n:40][cH:41]3)[c:17]2[CH2:18]1)[CH2:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1

참가 물질

반응물 2

HCID 595599905-bromo-N,N-dimethylpyrimidine-2-carboxamide

HCID 66813495N,N-dibenzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-chromen-3-amine

생성물 1

HCID 1454985425-[3-(dibenzylamino)-3,4-dihydro-2H-chromen-5-yl]-N,N-dimethylpyrimidine-2-carboxamide

출처 및 근거

ORD 기록: ord-1a53e20819194ed29735fcf59846450b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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