2-Fluoro-5-methoxyphenylboronic acid → 3-[3-(2'-Fluoro-5'-methoxy-2-trifluoromethoxy-biphenyl-4-ylmethoxy)-phenyl]-propionic acid

반응식

[Cl:1][c:2]1[c:3]([O:21][C:22]([F:23])([F:24])[F:25])[cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][c:10]([CH2:14][CH2:15][C:16](=[O:17])[OH:18])[cH:11][cH:12][cH:13]2)[cH:19][cH:20]1.[F:26][c:27]1[c:28]([B:35]([OH:36])[OH:37])[cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]1>>[c:2]1(-[c:28]2[c:27]([F:26])[cH:32][cH:31][c:30]([O:33][CH3:34])[cH:29]2)[c:3]([O:21][C:22]([F:23])([F:24])[F:25])[cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][c:10]([CH2:14][CH2:15][C:16](=[O:17])[OH:18])[cH:11][cH:12][cH:13]2)[cH:19][cH:20]1

참가 물질

반응물 2

HCID 41572112-Fluoro-5-methoxyphenylboronic acid

HCID 577060113-(3-(4-Chloro-3-(trifluoromethoxy)benzyloxy)phenyl)-propanoic acid

생성물 1

HCID 577061773-[3-(2'-Fluoro-5'-methoxy-2-trifluoromethoxy-biphenyl-4-ylmethoxy)-phenyl]-propionic acid

출처 및 근거

ORD 기록: ord-c57d1fa22d4340efa929fed32f79dee3
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…