N-methyl-2-pyrrolidone → 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile

HRID 2144908

반응식

HRID 2144908 반응식
[CH3:38][N:39]1[CH2:40][CH2:41][CH2:42][C:43]1=[O:44].[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:18]#[N:19])[cH:7][n:8][c:9]3[cH:10][c:11]([F:17])[c:12]([O:15][CH3:16])[cH:13][c:14]23)[cH:20][c:21]([O:25][CH3:26])[c:22]([Cl:24])[cH:23]1.[N:27]1([CH:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:18]#[N:19])[cH:7][n:8][c:9]3[cH:10][c:11]([N:35]4[CH2:34][CH2:33][CH:32]([N:27]5[CH2:28][CH2:29][CH2:30][CH2:31]5)[CH2:37][CH2:36]4)[c:12]([O:15][CH3:16])[cH:13][c:14]23)[cH:20][c:21]([O:25][CH3:26])[c:22]([Cl:24])[cH:23]1

참가 물질

4

반응물 3

HCID 13387N-methyl-2-pyrrolidoneHCID 787034-(1-Pyrrolidinyl)piperidineHCID 114861534-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrile

생성물 1

HCID 684604364-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile

출처 및 근거

ORD 기록
ord-0863d75a90ac4c49b66363da5663041a
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

연결된 노트

불러오는 중…