Dichloromethane → [6-(2-Hydroxy-pyrimidin-5-yl)-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

반응식

[B:39]([Br:40])([Br:41])[Br:42].[CH3:1][O:2][c:3]1[n:4][cH:5][c:6](-[c:9]2[c:10](-[c:29]3[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]3)[cH:11][c:12]([CH3:28])[c:13]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][CH:20]([N:23]4[CH2:24][CH2:25][CH2:26][CH2:27]4)[CH2:21][CH2:22]3)[n:14]2)[cH:7][n:8]1.[Cl:43][CH2:44][Cl:45]>>[OH:2][c:3]1[n:4][cH:5][c:6](-[c:9]2[c:10](-[c:29]3[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]3)[cH:11][c:12]([CH3:28])[c:13]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][CH:20]([N:23]4[CH2:24][CH2:25][CH2:26][CH2:27]4)[CH2:21][CH2:22]3)[n:14]2)[cH:7][n:8]1