2-Thiopheneacetyl chloride → N-[3-(3-{2-[(2-Methyl-1,2,3,4-tetrahydro-7-isoquinolinyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2-(2-thienyl)acetamide

반응식

[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][cH:26][c:27]4[c:32]([cH:33]3)[CH2:31][N:30]([CH3:34])[CH2:29][CH2:28]4)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1.[s:35]1[c:36]([CH2:40][C:41](=[O:42])[Cl:43])[cH:37][cH:38][cH:39]1>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][cH:26][c:27]4[c:32]([cH:33]3)[CH2:31][N:30]([CH3:34])[CH2:29][CH2:28]4)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1)[C:41]([CH2:40][c:36]1[s:35][cH:39][cH:38][cH:37]1)=[O:42]

참가 물질

반응물 2

HCID 1623622-Thiopheneacetyl chloride

HCID 59511387N-{4-[2-(3-Aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinyl}-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinamine

생성물 1

HCID 16749888N-[3-(3-{2-[(2-Methyl-1,2,3,4-tetrahydro-7-isoquinolinyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2-(2-thienyl)acetamide

출처 및 근거

ORD 기록: ord-f30cc6ad93454a55b8473486c52284e0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…