5-Iodosalicylic acid → Tert-butyl 4-(2-hydroxy-5-iodobenzoyl)piperazine-1-carboxylate

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:21][c:22]1[C:23]#[N:24].[OH:25][c:26]1[c:27]([C:28](=[O:29])[OH:30])[cH:31][c:32]([I:35])[cH:33][cH:34]1>>[N:8]1([C:28]([c:27]2[c:26]([OH:25])[cH:34][cH:33][c:32]([I:35])[cH:31]2)=[O:30])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]1

참가 물질

반응물 2

HCID 83885-Iodosalicylic acid

HCID 68766029Tert-butyl 4-(4-chloro-3-cyanobenzoyl)piperazine-1-carboxylate

생성물 1

HCID 31121968Tert-butyl 4-(2-hydroxy-5-iodobenzoyl)piperazine-1-carboxylate

출처 및 근거

ORD 기록: ord-d98f7040ee1046778cd98146f4fd75c1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

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