N-methyl-2-pyrrolidone → (3-{[(3-Benzyl-5-chloro-4-oxo-3,4-dihydro-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-cyclopropyl-methyl]-amino}-propyl)-carbamic acid tert-butyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][NH2:11])=[O:12].[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[n:20]1[c:21]([CH:31]([CH:32]2[CH2:33][CH2:34]2)[Cl:35])[n:22][n:23]2[c:24]([c:25]1=[O:26])[c:27]([Cl:30])[cH:28][cH:29]2.[CH3:36][N:37]1[CH2:38][CH2:39][CH2:40][C:41]1=[O:42]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][NH:11][CH:31]([c:21]1[n:20]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:25](=[O:26])[c:24]2[n:23]([n:22]1)[cH:29][cH:28][c:27]2[Cl:30])[CH:32]1[CH2:33][CH2:34]1)=[O:12]