참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1,5-Dichloroanthraquinone | HCID 6711 | — |
| 반응물 | 3-Amino-1-propanol | HCID 9086 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 9,10-Anthracenedione, 1,5-bis[(3-hydroxypropyl)amino]- | HCID 11314215 | — |
반응 단계
1,5-Dichloroanthraquinone (2.8 g; 10 mmol) is mixed with 3-amino-1-propanol (10 mL) in DMSO (50 mL) and heated to 130° C. for 4 hours. The mixture is cooled to ˜80° and added water (150 mL). When the mixture has reached RT the formed precipitate is isolated by filtration, washed with water (2×50 mL), boiled in toluene (200 mL) and the un-dissolved product is isolated by filtration and dried. Yield: 3.2 g (90%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08192937B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_06 |
|---|
| ORD ID | ord-f3325466c0ec494da3cb892c8ffb6c54 |
|---|
| 출처 메모 | uspto-grants-2012_06 |
|---|
