2-Chloropyridine-4-boronic acid → 2-(2-Chloro-pyridin-4-yl)-4-(3-methyl-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidine

반응식

[Cl:1][c:2]1[n:3][c:4](-[c:12]2[cH:13][c:14]([CH3:22])[c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1.[Cl:23][c:24]1[n:25][cH:26][cH:27][c:28]([B:30]([OH:31])[OH:32])[cH:29]1>>[c:2]1(-[c:28]2[cH:27][cH:26][n:25][c:24]([Cl:23])[cH:29]2)[n:3][c:4](-[c:12]2[cH:13][c:14]([CH3:22])[c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1

참가 물질

반응물 2

HCID 51515952-Chloropyridine-4-boronic acid

HCID 574686542-Chloro-6-(3-methyl-4-trifluoromethyl-phenyl)-4-trifluoromethyl-pyrimidine

생성물 1

HCID 574687672-(2-Chloro-pyridin-4-yl)-4-(3-methyl-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidine

출처 및 근거

ORD 기록: ord-904c9f501e2c4062a6372a7c81962e76
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

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