Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 178525098, 화합물 → HCID 178517868, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 178525098 | HCID 178525098 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178517868 | HCID 178517868 | 93% |
반응 단계
200 mg of Pd/C was added a solution of benzyl 2-(cis-4-hydroxycyclohexyl)-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate (2.13 g, 0.00551 mol) in methanol (50 mL) under nitrogen. The reaction mixture was stirred under an atmosphere of hydrogen for 3 hrs. The mixture was filtered, and the filtrate was concentrated to give 2-(cis-4-hydroxycyclohexyl)-2,8-diazaspiro[4.5]decan-1-one (1.29 g, 93%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08193207B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-b3c73d95de534f63806c88de073b99c9 |
| 출처 메모 | uspto-grants-2012_06 |