Tetrahydrofuran → Benzyl-4-(3-hydroxy-6-methoxy-2-methyl-1-oxo-4-phenyl-1,2,3,4-tetra-hydroisoquinolin-3-yl)piperidine-1-carboxylate

HRID 2159541

반응식

HRID 2159541 반응식
[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[O:32][C:33](=[O:34])[N:35]1[CH2:36][CH2:37][CH:38]([C:41](=[O:42])[Cl:43])[CH2:39][CH2:40]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:6]([C:7](=[O:8])[NH:9][CH3:10])[cH:11][cH:12]1.[CH:20]([Li:21])([CH2:22][CH3:23])[CH3:24]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:11][cH:12]1)[C:7](=[O:8])[N:9]([CH3:10])[C:41]([CH:38]1[CH2:37][CH2:36][N:35]([C:33]([O:32][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)=[O:34])[CH2:40][CH2:39]1)([OH:42])[CH:13]2[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1

참가 물질

5

반응물 4

HCID 8028TetrahydrofuranHCID 2776270Benzyl 4-(chlorocarbonyl)piperidine-1-carboxylateHCID 225559272-Benzyl-4-methoxy-N-methylbenzamideHCID 178418400CID 53628100

생성물 1

HCID 68433490Benzyl-4-(3-hydroxy-6-methoxy-2-methyl-1-oxo-4-phenyl-1,2,3,4-tetra-hydroisoquinolin-3-yl)piperidine-1-carboxylate

출처 및 근거

ORD 기록
ord-7adb2233450a4baea51919a65470645f
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

연결된 노트

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