Ethyl 2-(2-iminopyridin-1(2H)-yl)acetate hydrobromide → Imidazo[1,2-a]pyridin-2(3H)-one hydrobromide

HRID 215965노트

반응식

HRID 215965 반응식
[BrH:1].C([O:4][C:5](=O)[CH2:6][N:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]1=[NH:13])C>C(O)C>[BrH:1].[N:13]1[C:5](=[O:4])[CH2:6][N:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=12

참가 물질

3

반응물 1

HCID 68699194Ethyl 2-(2-iminopyridin-1(2H)-yl)acetate hydrobromide

생성물 1

HCID 44121307Imidazo[1,2-a]pyridin-2(3H)-one hydrobromide

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 9 g (34.4 mmol) of (2-imino-2H-pyridin-1-yl)-acetic acid ethyl ester hydrobromide salt in 200 mL of ethanol is heated at reflux for 18 h. The reaction mixture is then cooled to room temperature and the precipitate is collected. The isolated solid is washed with ethanol to give the desired compound.

후처리

  1. temperatureat reflux for 18 h
  2. customthe precipitate is collected
  3. washThe isolated solid is washed with ethanol

출처 및 근거

ORD 기록
ord-4312b25132944418ae79d67d6590fecd
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08193214B2

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