Water → N'-t-butyl-N-(thiobenzoyl)hydrazine

HRID 21625

반응식

HRID 21625 반응식
[C:1]([S:9]CC(O)=O)(=S)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[C:15]([NH:19][NH2:20])([CH3:18])([CH3:17])[CH3:16].O>N1C=CC=CC=1>[C:15]([NH:19][NH:20][C:1](=[S:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)([CH3:18])([CH3:17])[CH3:16]

참가 물질

5

반응물 3

HCID 962WaterHCID 70336((Phenylthioxomethyl)thio)acetic acidHCID 81889tert-Butylhydrazine monohydrochloride

생성물 1

HCID 19367775N'-t-butyl-N-(thiobenzoyl)hydrazine

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
120 °C

실험 절차

S-(thiobenzoyl)thioglycolic acid (3.0 g) was dissolved in 20 ml pyridine, treated with t-butyl hydrazine hydrochloride (excess, ca. 4 g) and then was heated at ca. 120° C. for 14 hours. Water (120 ml) was added and the mixture was extracted with ether. The organic extracts were dried over anhydrous magnesium sulfate, filtered and evaporated to give crude N'-t-butyl-N-(thiobenzoyl)hydrazine as a viscous yellow oil.

후처리

  1. extractionthe mixture was extracted with ether
  2. dry with materialThe organic extracts were dried over anhydrous magnesium sulfate
  3. filtrationfiltered
  4. customevaporated

출처 및 근거

ORD 기록
ord-6e222c5343aa4713879e968e86ac7513
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424333

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