Water → N'-t-butyl-N-(thiobenzoyl)hydrazine
반응식
[C:1]([S:9]CC(O)=O)(=S)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[C:15]([NH:19][NH2:20])([CH3:18])([CH3:17])[CH3:16].O>N1C=CC=CC=1>[C:15]([NH:19][NH:20][C:1](=[S:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)([CH3:18])([CH3:17])[CH3:16]참가 물질
5
반응 조건
- 온도
- 120 °C
실험 절차
S-(thiobenzoyl)thioglycolic acid (3.0 g) was dissolved in 20 ml pyridine, treated with t-butyl hydrazine hydrochloride (excess, ca. 4 g) and then was heated at ca. 120° C. for 14 hours. Water (120 ml) was added and the mixture was extracted with ether. The organic extracts were dried over anhydrous magnesium sulfate, filtered and evaporated to give crude N'-t-butyl-N-(thiobenzoyl)hydrazine as a viscous yellow oil.
후처리
- extractionthe mixture was extracted with ether
- dry with materialThe organic extracts were dried over anhydrous magnesium sulfate
- filtrationfiltered
- customevaporated
출처 및 근거
- ORD 기록
- ord-6e222c5343aa4713879e968e86ac7513
- 출처 데이터셋
- uspto-grants-1995_06
- 특허 번호
- US05424333
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