Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → 2-Chloro-10-(5-methyl-1-pyrrolin-2-YL)phenoxazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 5-Methyl-2-pyrrolidone | HCID 66055 | — |
| 반응물 | 2-Chlorophenoxazine | HCID 10632580 | — |
| 생성물 | 2-Chloro-10-(5-methyl-1-pyrrolin-2-YL)phenoxazine | HCID 22754262 | — |
반응 단계
Reaction of 2-chlorophenoxazine, 5-methyl-2-pyrrolidinone and phosphorus oxychloride according to the procedure of Example 1 provides the free base 2-CHLORO-10-(5-METHYL-1-PYRROLIN-2-YL)-PHENOXAZINE as a distillable oil, b.p. 150-170° C. at 0.1 mm Hg. Conversion of the free base to the hydrochloride salt affords 2-CHLORO-10-(5-METHYL-1-PYRROLIN-2-YL)PHENOXAZINE HYDROCHLORIDE, m.p. 213.5-215.5° C., as a crystalline solid in a 34% overall yield by refluxing with benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04132794 |
| 출처 데이터셋 | uspto-grants-1979_01 |
| ORD ID | ord-72071dc0f9514c0d9938464318c97a2a |
| 출처 메모 | uspto-grants-1979_01 |