Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
9,9-Dimethyl-9,10-dihydroacridine → 9,9-Dimethyl-10-(5-methyl-1-pyrrolin-2-YL)acridan
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 9,9-Dimethyl-9,10-dihydroacridine | HCID 22647 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 5-Methyl-2-pyrrolidone | HCID 66055 | — |
| 생성물 | 9,9-Dimethyl-10-(5-methyl-1-pyrrolin-2-YL)acridan | HCID 3044167 | 11% |
반응 단계
Reaction of 9,9-dimethylacridan, 5-methyl-2-pyrrolidinone and phosphorus oxychloride according to the procedure of Example 1 provides the free base 9,9-DIMETHYL-10-(5-METHYL-1-PYRROLIN-2-YL)ACRIDAN as a distillable oil, b.p. 160-180° C. at 0.15 mm Hg. in 11% yield. Conversion of the free base to the hydrochloride salt affords 9,9-DIMETHYL-10-(5-METHYL-1-PYRROLIN-2-YL)ACRIDAN HYDROCHLORIDE, m.p. 232.5-234.5° C. (dec.) (corr.), by trituration with hot benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04132794 |
| 출처 데이터셋 | uspto-grants-1979_01 |
| ORD ID | ord-30e420669ce646099f91383062b5a813 |
| 출처 메모 | uspto-grants-1979_01 |