2-(Ethylthio)ethanol → 2-(Ethylthio)ethyl 2-chloroethanesulfinate

HRID 2163429노트

반응식

HRID 2163429 반응식
[OH:1][CH2:2][CH2:3][S:4][CH2:5][CH3:6].[Cl:7][CH2:8][CH2:9][S:10](Cl)=[O:11]>CCOCC>[Cl:7][CH2:8][CH2:9][S:10]([O:1][CH2:2][CH2:3][S:4][CH2:5][CH3:6])=[O:11]

참가 물질

4

반응물 2

HCID 80752-(Ethylthio)ethanolHCID 125500522-Chloroethanesulfinic chloride

생성물 1

HCID 227516332-(Ethylthio)ethyl 2-chloroethanesulfinate

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

A solution of ethyl 2-hydroxyethyl sulfide (10.6 w) in dry ether (50 v) was slowly added to 2-chloroethanesulfinyl chloride (14.7 w) in dry ether (200 v) maintained at about -10° under a nitrogen atmosphere. Upon warming to ambient temperature, the reaction mixture was evaporated under reduced pressure. The residual oil was passed through a wiped film molecular still to yield 2-(ethylthio)ethyl 2-chloroethanesulfinate (15.4 w) boiling at 95-100° under reduced pressure (1 × 10-4 torr).

후처리

  1. temperaturemaintained at about -10° under a nitrogen atmosphere
  2. customthe reaction mixture was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-52b74871f0cc4aef9636860c257edd9a
출처 데이터셋
uspto-grants-1979_01
특허 번호
US04134752

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